The dead include a man in his 80s from Prairie Mountain Health linked to a the B.1.1.7 variant of concern, a woman in her 20s for the Winnipeg health region, and a man in his 70s from Winnipeg linked to the B.1.1.7 variant of concern.
Provincewide, two-thirds of the variant cases are the B117 variant originally detected in the United Kingdom, while just over a third are listed as unspecified.
The provincial test positive rate rose from 8.8 percent to 9.1 percent.
The province said more details will be released in the coming days.
All Manitobans, aged 35 and older, can now receive a COVID-19 vaccination.
The latest update comes hours after Chief Provincial Public Health Officer Dr. Brent Roussin announced new pandemic rules on Friday evening.
Restaurants, bars and patios will close to in-person dining but can still provide take-out and delivery services.
The other new cases announced Saturday are split between the Southern Health region (which reported 43), the Prairie Mountain Health region (30), the Interlake-Eastern health region (17) and the Northern Health Region (nine).
More contagious coronavirus variants have become more dominant in recent weeks, and the total number of variant-linked cases jumped by 214 on Thursday to 3,003.
Of Manitoba's 2,732 active cases, 1,025 are variants.
School cases have dropped slightly since the last provincial update, but they are high: 213, or a quarter, of Manitoba schools now have at least one case.
The number of mannitophanes in the hospital due to COVID-19 increased slightly to 185 and those in intensive care increased from 47 to 52.
Sixteen of the 986 COVID-19 deaths in Manitoba are related to coronavirus variant infections, up from 12 on Wednesday.
Manitoba has now identified 41,425 cases of the illness to date, including 37,198 people who have been deemed recovered.