Seventeen states and the District of Columbia have laws similar to California's current restraining order law, but the new law that takes effect on January 1 will be broader.
Golden State lawmakers had made repeated efforts to pass the ban in previous years, but had consistently been stymied by Newsom's, predecessor, Gov.
Several Republican-led states, including Georgia, Kentucky and MS, have passed laws banning abortions once a fetal heartbeat is detected.
"As other states and the federal government go backward, restricting reproductive freedom, in California we are moving forward, expanding access and reaffirming a woman's right to choose", Newsom said.
"With school and workplace shootings on the rise, it's common sense to give the people we see every day the power to intervene and prevent tragedies", said the bill's author, Democratic Assemblyman Phil Ting of San Francisco.
"We can not allow this type of abuse to occur in California", Hueso said, according to a legislative analysis of the proposal that eventually became law.
Lila Rose, president of the anti-abortion group Live Action, tweeted that with the bill's signage, "Instead of empowering women with life-affirming options, CA is telling young women they aren't strong enough to succeed without killing their children". "Where is the help for those women?"
The abortion pill - "medication abortion" or "chemcial abortion" - is actually two pills, one to deprive a developing pre-born baby of the nutrition he needs and then one to induce contractions.
More than 400,000 women attend public universities in the state.
According to a study in the Journal of Adolescent Health, about 62% of students at California universities were more than 30 minutes away from the closest abortion facility using public transportation.
California has banned smoking on beaches and in state parks.
University of California spokeswoman Sarah McBride said the university "believes students should have access to affordable and convenient reproductive health care of their choosing".
The Democratic governor also signed a law that will limit Californians to purchasing one long rifle per month, according to The Sacramento Bee.