US military health officials have issued an alert recommending that service members and their families refrain from vaping, after the Centers for Disease Control and Prevention linked 380 cases of severe lung disease, including six deaths, to the habit.
Now, the Center for Disease Control and Prevention (CDC) is conducting thorough research and urging people to stop using the devices.
The deaths, previously reported, were in California, Illinois, Indiana, Kansas, Minnesota and Oregon. Symptoms include chest pain, chronic cough and difficulty breathing.
While an investigation is ongoing, the CDC reminds people that there is a lot of lacking information on what substances are causing these cases and which products are most risky.
Three of the patients also used nicotine-cigarettes, and two smoked marijuana or traditional cigarettes.
Recent data claims that while the overall teen smoking rate is at an all-time low, 20 percent of high school students and 5 percent of middle schoolers use e-cigarettes.
And there is "substantial evidence" that the vapor contains traces of metals, either from the coil used to heat the liquid or from other parts of the device.
The liquids however contain highly addictive nicotine.
NY officials have been focused on a substance called vitamin E acetate, which recently has been used as a thickener, particularly in black market vape cartridges that also contain THC.
In response to the outbreak, President Donald Trump and the US Food and Drug Administration announced on Wednesday a ban on flavored vaping products - aside from tobacco - from store shelves. Most of the products tested had THC and other compounds found in marijuana plants, and most samples had vitamin E oil additives, Moore said.
One doctor in North Carolina said all five of the state's cases involved patients vaping THC products that were purchased on the street.
Acute lipoid pneumonia occurs when tiny particles from fat or oil enter the lungs and inflame the lining.
Incidents of lung-disease and death around the country has 33 states urgently seeking answers.
But the bulk of this research was carried out before the current outbreak of severe lung disease in the United States, with more than 450 cases now under investigation.
Ann Scales, spokesperson for the Massachusetts Department of Public Health, said then that no confirmed cases related to severe lung disease associated with electronic-cigarette product use to date in the state, but "several suspect cases being investigated".