The final starts at 14:00 BST.
With Williams serving to take the first set, Strycova managed two break points before the seven-time Wimbledon champion blasted an ace pact Strycova to take Set 1 in just 27 minutes.
Svitolina, seeded eighth here at Wimbledon and playing in her first grand slam semifinal, put up more of a fight in the second set but was powerless against the Romanian's thundering ground strokes.
The Romanian won the French Open a year ago and has reached the final at Roland Garros on two other occasions. Halep has lost nine of her last 12 final appearances overall.
Mouratoglou says that's behind her now, and she has no plans of slowing down.
"I respect a lot what she has done and what she's doing", said Halep, who, like Williams, used to be ranked No. 1. "But it's definitely an effort". Not getting over-pumped, but at the same time not getting under-wound. "I have to be in that right space". This is her first Wimbledon final. We will see what is going to happen.
Over the years, she's recovered from muscle injuries, ankle injuries, back injuries, elbow injuries and, as recently as this spring, a knee injury. "I've had some big ones", said Williams, whose fastest delivery so far stands at 122mph.
After a three-set struggle against Alison Riske in the quarter-finals Tuesday, Williams was dominant against Strycova, who was limited by a leg muscle problem that cropped up in the very first game.
How can Halep stop her?"It's one of the best moments of my life". I have a great job and I am still pretty good at it. The rallies were very long and very powerful, as well.
Svitolina, seeded No. 8, had never been to the final four at any Slam before this tournament. "It was just important to always try to better yourself in any way that you can".
"Serena has to be worn out to take some of the sting out of her serve". "You feel like you are moving backwards because the ball is coming at you so hard". In the victory, Halep won 74 percent of her first serve points and 44 percent of her second serve points.
Williams will hope for a happier ending than being out-played both by Angelique Kerber in last year's Wimbledon final and Naomi Osaka in the US Open final where a spectacular meltdown torpedoed her cause, leading her to eventually consult a therapist.
Her Roland Garros title defence ended with a straight-set defeat by unseeded American teenager Amanda Anisimova. No one in the draw has hit more than her 45 aces but, for someone who red-lines her power at around 120mph, she has logged surprisingly few double-faults: 11, in fact, which is a risk-reward ratio of about four to one.
"I actually didn't think about it since because it's really not about 24 or 23 or 25. She wants to prove that she can do it again", Williams said.