The freight train was standing on the loop line when the speeding passenger train instead of running on the mainline went on the wrong track.
On June 20, at least three people, a train driver, and two assistant drivers were killed and several others injured after a passenger train collided with a freight train near Hyderabad.
The injured were taken to a nearby government hospital and to a more advanced facility in Rahim Yar Khan, hospital officials said.
Up to four passenger cars have derailed as a result of the collision, the broadcaster added.
Television footage from the site showed the heavily damaged locomotive and carriages, as emergency workers and local people used metal-cutting tools and heavy cranes.
Senior police official Umar Salamat told local media the collision took place because the passenger train was diverted onto the incorrect track at the station, hitting the parked freight train.
Prime Minister Imran Khan has ordered authorities to provide the best possible medical care to the victims and said he was saddened by the news.
The cause of the crash is under investigation.
The minister also announced compensation for the dead and injured.
"PM Imran Khan has been proud of his decision to give this ministry to Sheikh Rasheed".
Pakistan has a long history of train and road accidents, mainly due to poor infrastructure and a lack of safety standards.
A National Assembly standing committee was recently told that there have been 384 train accidents in Pakistan since 2014: 74 in 2018-19, 67 in 2017-18, 78 in 2016-17, 76 in 2015-16, and 89 accidents in 2014-15.