Various emergency services were involved in the incredible rescue.
"Rescue workers are busy trying to get to the baby at the moment", said Rescue Care's operations director, Garrith Jamieson.
The baby, believed to be a girl, was stabilised at the scene and loaded into a medical helicopter and taken to a hospital.
Despite the efforts of paramedics, the baby died.
Medics said she may be suffering from hypothermia but otherwise appeared unhurt. This was the site where emergency services conducted a harrowing three-hour rescue of a newborn baby girl with the placenta still attached, who had been trapped down the drain. She is basically stable enough for transfer to one of the base hospitals where they can sort out the social side.
Police are investigating the matter.
Mr McKenzie said when rescuers first arrived she was around 6ft down the drown but was then washed about 18ft further down the 1ft diameter drain.
KZN EMS spokesperson Robert McKenzie said: "It's good news for the ending of this rescue today". The community was also very supportive and helpful which was great'.