The four-time All Pro has already dealt with an ankle injury this season, but has yet to miss a game.
Gronkowski, 29, has played in every game this season for the Patriots, who are 4-2 and tied for first place with the Dolphins in the AFC East.
The tight end has 26 receptions for 405 yards and one touchdown. Those numbers aren't especially prolific by his high standards, but Gronkowski's importance to the offense was evident when Tom Brady went his way in the final, critical moments of the Chiefs game last Sunday.
With multiple important players on the injury report, Tom Brady and the Patriots are going to face one of the best defenses in the National Football League in the Chicago Bears at less than 100 percent.