But HBO bagged the coveted best drama prize.
She also used the opportunity to rally people to vote. "SNL" faux news anchors Michael Che and Colin Jost were hosts and mocked numerous nominated shows and actors.
"Game of Thrones" was ultimately the biggest victor of the night, returning to the drama series race after sitting out last year with 9 wins total this year.
HBO dark comedy Barry notched two acting wins - for Winkler and series star Bill Hader. "We solved it!" crooned Saturday Night Live nominees Kate McKinnon and Kenan Thompson, with back-up from pop stars John Legend and Ricky Martin - and even RuPaul.
In her acceptance speech, Borstein thanked Amazon and Amy Sherman-Palladino, the creator of The Marvelous Mrs. Maisel, who won the Emmy award for both Outstanding Writing for a Comedy Series and Outstanding Directing for a Comedy Series.
Another recipient with local roots was comedian John Mulaney, victor of the variety special writing award for his Netflix stand-up special "Kid Gorgeous at Radio City". Unlike many other news organizations, we have not put up a paywall.
"I'll be thanking you for the rest of my life for trusting me with your Midge", she said, referencing her character.
Regardless of the total number of wins, the nominations alone marked a major milestone for Netflix.
Saturday Night Live creator Lorne Michaels accepts the Emmy for Outstanding Variety Sketch series. The networks, which air the Emmy telecast on a rotating basis, are so eager for the ad dollars it generates and its promotional value for fall shows that they endure online competitors sharing the stage.
The Assassination of Gianni Versace took the Emmy for best-limited series and brought an acting trophy for Darren Criss, who played the gay serial killer who murdered the Italian designer in Miami in 1997. FX hit show, Atlanta, which is created & starred in by Donald Glover, was up for "Lead Actor in a Comedy Series", but unfortunately Donald didn't win.
'I love you and I share this with you because you're an unbelievable handsome brother.