Osaka said during the interview that she initially didn't know what was going on because she turned away from the scene as Williams approached Ramos and started yelling.
Ramos is deemed one of the more experienced umpires in the game with nearly 30 years of experience but for overseeing the Grand Slam final he received a fee of just £370 - a standard daily rate.
"For me, it's just who I am, so when someone asks me a question like that it really throws me off, because then, I really have to think about it", she said.
Despite US players and captain Jim Courier declaring they have no issues with Ramos umpiring their matches, Adams can't be thrilled about facing Ramos so soon after siding with Williams in the wake of the US Open women's final. Williams was outraged, and demanded an apology, telling Ramos that "I don't cheat to win, I'd rather lose".
Britain's Jamie Murray has rejected claims of men being treated more leniently than women by umpires.
Mouratoglou admitted afterwards that he had tried to coach Williams, who said she never saw the Frenchman's gestures.
But the International Tennis Federation defended Ramos and said in a statement that his "decisions were in accordance with the relevant rules" and that he "acted at all times with professionalism and integrity". She said on Tuesday both sides shared the blame for the incident. "I also could sympathize, because I've been a fan of Serena my whole life, and I knew how badly the crowd wanted her to win".
The United States Tennis Association (USTA) and Women's Tennis Association (WTA), however, supported Williams' accusations that Ramos' actions were based in sexism.
"It's an unhappy situation but à la carte refereeing doesn't exist", added the 47-year-old seasoned umpire. Ramos, meanwhile, was paid £370 ($480) as a "standard daily rate" for umpiring, The Times says. The third and final penalty came as Williams continued to castigate the umpire, saying, "You stole a point from me".