But for a Moussa Sissoko chance in the 56th minute, blocked by a superb reflex save by Dubravka, Mauricio Pochettino's side struggled to create chances in the second half.
Newcastle immediately responded when Joselu headed in the equalizer just two minutes later.
Atsu did not have the same impact that Ritchie had for Newcastle on the wing, but Muto was playing with the urgency that Perez lacked. [We are] giving out supporters another hard season when we move to the new stadium.
For only the second time in Premier League history, Newcastle haven't named a debutant in their starting XI on the opening day.
For Spurs, World Cup-winning captain Hugo Lloris started in goal, joined in the line-up by Jan Vertonghen, Eric Dier, Dele Alli, Christian Eriksen and England captain Harry Kane. "But what happens with Harry is that he can not score three goals in every game", Pochettino added.
The only surprise was that, after Alli's 18th-minute strike that turned out to be the victor, there was no further scoring with both goalkeepers, Slovak Martin Dubravka and Frenchman Hugo Lloris, forced to make a string of impressive saves.
"If we are happy with our squad and can not improve our squad, sometimes it's better to keep our squad together".
Meanwhile Tottenham, fielding several of their World Cup stars including England's Harry Kane and Dele Alli, grew stronger as the game progressed.
In a contest where most of the football was played in the final third at both ends, it was Alli's defensive work that impressed, as well as his clever finish.
The Frenchman was fortunate, however, as Kenedy's control let the Brazilian down at a crucial point, when a more assured first touch would have put the on-loan Chelsea midfielder in on goal.