The family said in a statement late Saturday that the novelist had died at his London home.
His first book, The Mystic Masseur, was published in 1951 and a decade later he published his most celebrated novel, A House for Mr Biswas, which took over three years to write.
Vidiadhar Surajprasad Naipaul wrote more than 30 books and won the Nobel Literature Prize in 2001.
In awarding him the $1 million Nobel Prize in Literature in 2001, the Swedish Academy praised Naipaul for combining genres into his own style that compels readers "to see the presence of suppressed histories".
His first wife, Patricia Hale, died in 1996 and he went on to marry Pakistani journalist, Nadira.
Among his other well-known works were those on Islamic fundamentalism - the 1981 work Among The Believers and the 1998 book Beyond Belief. Naipaul's nonfiction often provoked much anger, and many were offended by his views about Islam and India - Rushdie, for example, thought Naipaul was promoting Hindu nationalism.
Writer V.S. Naipaul waits to receive his Nobel prize for literature at Stockholm's Konserthuset from Sweden's King Carl Gustaf, Sweden December 10, 2001.
As his literary stature grew, so did his reputation as a hard, irascible personality.
Naipaul ignored Theroux's book, but he did authorise a candid biography that confirmed some of Theroux's claims.
Reports out of the United Kingdom quotes his wife, Lady Naipaul, as confirming his death.