President Jimmy Morales has called for three days of national mourning following what officials say is the volcano's most intense eruption in more than four decades.
Guatemalan authorities increased the confirmed death toll from the eruption of the Fuego volcano (or Volcano of Fire) to 69 as officials suspended the search until dawn on Tuesday.
One of Central America's most active volcanos, the conical Vocano of Fire reaches an altitude of 12,346 feet (3,763 meters) above sea level at its peak. "I think they ended up buried", Consuelo Hernandez, a resident of the village of El Rodeo, told the newspaper Diario de Centroamerica.
Walter Cotte, Regional Director of Americas for the International Federation of Red Cross and Red Crescent Societies (IFRC), said: "This disaster is very serious, and the situation may get even worse - as well as the ongoing eruption, communities are also at high risk of mud avalanches". Conred said 3,271 people had been evacuated.
Later, 18 bodies are said to have been found in the village of San Miguel Los Lotes.
Search and rescue operations were suspended due to low light and risky conditions but were to resume early on Monday morning, he said.
At least seven people have been killed and 20 more injured by Sunday's eruption of the Volcan de Fuego, which lies about 27 miles (44 kilometers) southwest of Guatemala City.
Dozens of videos appeared on social media and Guatemalan TV showing the extent of the devastation.
Flows of lava have reportedly struck at least one village, causing deaths and injuries.
In the village of El Rodeo, people said they did not learn of the danger until it was too late.
Ms Lopez's husband, Joel Gonzalez, said his father had been unable to escape and was believed to be "buried back there, at the house".
Volcanic ash covers parked motorcycles, brought by the Fuego Volcano, in Antigua Guatemala. Guatemala City's La Aurora global airport have been shut down due to the presence of volcanic ash on the runway, which may cause an accident.
Workers and guests were evacuated from the La Reunion golf club. "We saw the lava was pouring through the corn fields and we ran towards a hill".
Kilauea's primary mode of destruction is lava, but Fuego has unleashed pyroclastic flow - a nasty mix of ash, rock and volcanic gases that can be much more unsafe than lava.
FILE: Police officers wearing face masks guard the area after Fuego volcano erupted violently in El Rodeo, Guatemala, 3 June 2018.
"Temperatures in the pyroclastic flow can exceed 700 degrees (Celsius) and volcanic ash can rain down on a 15 kilometer (9.32 miles) radius". As of Monday morning, volcanic activity had subsided, according to Guatemala's National Institute of Seismology, Vulcanology, Meteorology and Hydrology.