He turned himself into a NY police station before being charged with first and third degree rape in 2013, seemingly in a Midtown Manhattan hotel, and a criminal sex act in the first degree in 2004.
Weinstein left the station in handcuffs and was taken to a courthouse where he gave up his passport.
As he surrendered, Weinstein found himself surrounded by lights and cameras in a spectacle he couldn't control.
Earlier, he entered a police station carrying books that harkened to his show business roots: one on the Broadway songwriting team of Rodgers and Hammerstein, and another about famed film director Elia Kazan.
Film producer Harvey Weinstein leaves the 1st Precinct in Manhattan in NY on May 25, 2018.
He appeared in court later and was charged with assaulting Lucia Evans, who told investigators he forced her to perform oral sex on him in 2004. She was among the first women to speak out about the producer.
Law enforcement officials did not immediately identify the two women who Weinstein is charged with attacking.
Evans, now a marketing consultant, told The New Yorker that Weinstein approached her in a club in 2004 and assaulted her in a Tribeca office. And in 2015, an Italian model went to New York City police and accused him of groping her during a meeting. The detective also said that in 2013, Weinstein kept a woman in a room against her will "and engaged in sexual intercourse with informant by forcible compulsion", even though she had "clearly expressed her lack of consent to the act".
"To see him do the Bill Cosby old man perp walk on the way in...that's a very good thing", McGowan added. He will wear an electronic monitoring device at all times, and face other travel restrictions. The film producer has until next week to decide whether to tesitfy before a grand jury.
The #MeToo campaign against sexual harassment and abuse swept through Hollywood last autumn, in the wake of the accusations against Mr Weinstein. Prosecutors in the office of the Manhattan district attorney Cyrus Vance conducted dozens of interviews in NY and elsewhere and issued hundreds of subpoenas, and their inquiry is not over. That investigation is in its preliminary stages.
Weinstein stands accused by more than 70 women of sexual misconduct, including rape, with some of the accusations going back decades. Several actresses and models accused him of criminal sexual assaults, but numerous encounters happened too long ago for any prosecution.
Actress Rose McGowan, among the first to accuse Weinstein of sexual assault, said seeing images of him in handcuffs was surreal. In the retrial, the judge allowed five other accusers to tell similar stories of alleged abuse by the former TV star. Because it's all true.
"I don't want to, because it's not about me", she replied.
The statute of limitations for rape and certain other sex crimes in NY was eliminated in 2006, but not for attacks that happened prior to 2001.
The rape charges involve a woman who has not come forward publicly.
Weinstein was a fixture of elite Manhattan and Los Angeles society until his accusers came forward.