We can not guarantee that it is suitable for the visually or hearing impaired. "We still have two ambulances at the site because there might be more people under the rubble", Dr Nehmat Barak, chief of the Mirwais Hospital in Kandahar, said.
Another witness said he was inside his shop when the explosives detonated.
The NDS intelligence service said the minibus was discovered in a large open yard of mechanics workshops but blew up before it could be defused, Reuters reports.
Witnesses said fix crews were at the site, clearing large quantities of rubble and debris from the explosion.
No individual or group has so far claimed responsibility behind the incident.
Police officers keep watch while a man drives his damaged vehicle at a auto bomb attack site in Kabul, Afghanistan January 27, 2018.
Many have been in the capital, Kabul, but provincial cities have also been hit as the Taliban, seeking to reimpose hardline Islamic rule, have stepped up fighting across the country. "As the security forces were trying to defuse the [explosives in the] van, it detonated", said police spokesperson Mohammad Qasim Azad.
At least 32 people have been reported killed in an explosion in southern Afghanistan and attacks in the country's east, as the Taliban pushed ahead with its annual spring offensive across the country.
Last week the insurgent group attacked western Farah city, but were repelled by commandos backed by the Afghan and US Air Force. Mujahid claimed the Jaghatu district headquarters was captured as well as police checkpoints in Dih Yak.
Security officials say violence is expected to pick up as preparations continue for parliamentary elections scheduled for October.