Sheeran's Divide album emulated Dua Lipa's score minus the breakthrough act, which he no longer qualifies for. The UK songstress, who is the most streamed female artist on Spotify in 2017 in UK, will perform hits from her Gold selling first album at the du Forum, Yas Island in Abu Dhabi on Saturday, February 24, presented by du LIVE! and brought to you by FLASH Entertainment.
Singer-songwriter Sampha, who won the Mercury Prize past year, competes with Dua Lipa and rappers J Hus, Loyle Carner and Dave in the British breakthrough act category.
Sheeran received a third nomination in best British video, again for "Shape of You", and is joined in the category by Dua, Clean Bandit and Zara Larrson, Calvin Harris, Anne Marie, Zayn Malik and Taylor Swift, Little Mix and Jonas Blue.
In the best British band category, the return of Damon Albarn's Gorillaz sees the animated outfit nominated alongside London Grammar, Wolf Alice, The xx and Royal Blood.
Foo Fighters - who are confirmed to perform at this year's ceremony - are up against Arcade Fire, The Killers, LCD Soundstyem and HAIM for best global band.
The singer-songwriter, who hails from Framlingham and went to Thomas Mills High School, will compete with a quartet of debut albums including Stormzy's Gang Signs And Prayer and Rag'N'Bone Man's Human.
Taylor Swift, Lorde, Bjork, Pink and Alicia Keys are up for best global female, while Childish Gambino, Beck, DJ Khaled, Drake and Kendrick Lamar are up for best worldwide male.
At the ceremony to announce the nominations, Jorja Smith was also revealed as the victor of the 2018 critics' choice BRIT Award.
The news comes on the back of the 22-year-old leading the Brit Award nominations with nods for best female, best video, best single and British breakthrough artist.