"When you look at their results, their form, the team they have got and the belief in the camp, it has got to be their best opportunity". Factor in that the club is still alive on three other fronts-FA Cup, League Cup, Champions League-and the potential for a truly special season remains tantalizingly alive.
After initially refusing to entertain the thought, Pep Guardiola's subtle remarks surrounding Arsenal's unbeaten Premier League campaign of 2003-04 left fans and pundits alike wondering whether the record was now on his mind.
With Liverpool perhaps standing as the most similar team to Guardiola's oppressive City in terms of style and approach, Sunday's clash will fall into the favour of whichever side can consolidate their methods quickest.
How can Liverpool beat City? They will also be hoping to show off their new £75-million asset - Virgil van Dijk.
The Reds boss was pleased to confirm a major boost with the news that Mohamed Salah is set to be passed fit to face City this weekend after recovering from a groin strain.
It was distorted by Sadio Mane's first-half dismissal and, while Liverpool's 10 men were unable to formulate an answer to City, part of the intrigue lies in the question of what will happen if both sides play progressive, pressing games at pace for 90 minutes.
Said game aside however, the state of play is rather an interesting one. It's worth noting that this game could very well be postponed. Since December 23, City have registered five wins and a draw in all competitions and only three goals have been conceded during that period, but the manner of some of their recent results suggests that there are chinks in their armour which can be exposed by the Merseyside giants, who will meet high-press with high-press.
Arsenal host City next month, but given their latest crisis, it is not easy to envisage them being the team to stop City.
And yet there seems to be ever fewer games when City could lose.
"Maybe Arsene (Wenger) is anxious about that, but I tell him many times: 2004, that run is for him".
Unbeaten City are 15 points clear at the top of the table, having scored more goals than anybody, with 64, but fourth-placed Liverpool come second on that count with 50.
The German will reveal more on Moreno's fitness and issue an update on the shape of the rest of his first-team squad in his pre-City address to the media on Friday.
While Van Dijk will win the physical element of this one all day long, a single lapse in concentration would more than likely see Aguero dish instant punishment and put City out of reach.
City's style of play could also prove telling down the line.